Drexel University Team Duplicates Dr Alan MacDonald’s Findings of Bacterial Biofilms in Alzheimer’s Plaques

Dr. Herbert B. Allen and his colleagues at Drexel University, Philadelphia have confirmed the presence of bacterial biofilm substance in autopsy brain tissue from victims of Alzheimer’s disease.

The extracellular polysaccharide matrix of the biofilms was detected using periodic acid Schiff (PAS) stain, and co-localised with the beta-amyloid in the plaques, which are the hallmark of Alzheimer’s.

In summer 2015, in a groundbreaking series of experiments, Dr. Alan MacDonald found Borrelia biofilms in 1000 consecutive Alzheimer’s plaques from a series of five patients’ hippocampal specimens. (The hippocampus, a memory centre , is one of the most catastrophically affected regions of the brain in Alzheimer’s.)

Borrelia miyamotoi is classified as a relapsing-fever type bacteria, but is associated with Lyme disease. Biofilms of this bacteria were identified by Dr. MacDonald using highly specific Molecular Beacon DNA probes for Borrelia which he had recently developed. The biofilms were shown to occupy exactly the same areas as the Beta-amyloid in the plaques with the help of Congo red and/or Thioflavin T stains for amyloid.

The work of Dr. Allen’s team further confirms the many findings by Dr. Alan MacDonald and Dr. Judith Miklossy over the years implicating spirochaetes in Alzheimer’s, a soul-destroying illness afflicting tens of millions worldwide.

The beta-amyloid plaques have long been presumed by the medical establishment to be the cause of the dementia in Alzheimer’s. But the microscope now tells a different story.

A number of scientists are now advancing the theory that the beta-amyloid may actually be an anti-microbial peptide deployed by the body in defense against infection.

Please click here to view the article in the Journal of Neuroinfectious Diseases by Dr. HB Allen et al.

A report on Dr. MacDonald’s 2015 work complete with striking pairs of micrographs illustrating the co-location of amyloid and Borrelia biofilm can be found here.